Glabridin, a Stable Flavonoid of Glycyrrhiza glabra: HPTLC Analysis of the Traditional Formulation
作者： Mhaveer Singh , Yunus Kamal , Ennus Tamboli , Rabea Parveen , Shahid Ansari
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摘要: A novel HPTLC method has been developed for the estimation of glabridin in Licorice rhizome and its Unani polyherbal formulation (Qurs-e-Gul). Separation was achieved on silica using toluene, dichloromethane, ethyl acetate equal ratios. compact, well resolved peak with RF value 0.56 ± 0.02 observed. Calibration curve revealed a good linear relationship r2 0.993 between area concentration range 25–500 ng spot−1. The proposed validated as per International Conference Harmonization (ICH) guidelines. stability assessment carried out by studying degradation stressed acid, base, oxidation, thermal, humidity. Photodegradation also after keeping drug sunlight, dark, UV lights. can be used routine determination crude drugs herbal formulations containing one ingredients, quality control stabilit...
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