Tendon cell ciliary length as a biomarker of in situ cytoskeletal tensional homeostasis.
作者： Michael Lavagnino , Steven Paul Arnoczky , Aleksa Michele Sedlak , Keri Gardner
DOI: 10.11138/MLTJ/2013.3.3.118
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摘要: To determine if tendon cell ciliary length could be used as a biomarker of cytoskeletal tensional homeostasis, 20 mm long adult rat tail tendons were placed in double artery clamps set 18 apart to create 10% laxity. The allowed contract over 7 day period under culture conditions. At 0, 1, 5, and days the cilia stained measured using confocal imaging. There was significant (p<0.001) increase at 1 day. 5 (when became visibly taut) there decrease compared 1. By remained taut returned zero values (p=0.883). These results suggest that reflects local mechanobiological environment cells potential situ altered homeostasis.
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