Avoiding Trouble Down the Line: The Management and Prevention of Hemodialysis Catheter-Related Infections

作者: Charmaine E. Lok

DOI: 10.1053/J.ACKD.2006.04.009

关键词:

摘要: Over the last 2 decades, hemodialysis catheter use has increased. Annually, approximately 30% of patients using a central venous (CVC) experience septic or bacteremic episode and are subsequently at risk its associated long-term complications mortality. Because serious clinical financial impact catheter-related bacteremias (HCRIs), standardized, validated definitions based on patient population necessary in order to better diagnose, monitor, report HCRI for quality assurance research purposes. The pathophysiology involves complex interaction between triad that consists host patient, infecting microorganism, vehicle catheter. Although microorganism contribution pathogenesis is likely most important, certain characteristics may be more amenable manipulation. key managing prophylaxis against initial adherence subsequent biofilm development. General specific prophylactic maneuvers directed both an intravascular extraluminal route entry discussed including antibiotic- silver-impregnated catheters dressings, subcutaneous access devices, topical exit site. In addition systemic antibiotic use, 3 methods HRCI treatment salvage, guidewire exchange, concurrent lock compared. outcome highlight importance careful, continual infection surveillance. multidisciplinary control team desirable, staffing education physician feedback have been shown improve guidelines reduce HCRI.

参考文章(150)
John Dunn, William Nylander, William Nylander, Robert Richie, Robert Richie, Central venous dialysis access: Experience with a dual-lumen, silicone rubber catheter Surgery. ,vol. 102, pp. 784- 789 ,(1987) , 10.5555/URI:PII:0039606087901565
M. Khandelwal, S. Bailey, S. Izatt, M. Chu, S. Vas, J. Bargman, D. Oreopoulos, Structural changes in silicon rubber peritoneal dialysis catheters in patients using mupirocin at the exit site. International Journal of Artificial Organs. ,vol. 26, pp. 913- 917 ,(2003) , 10.1177/039139880302601007
J R Kirkpatrick, S C Bonawitz, E J Hammell, Prevention of central venous catheter sepsis: A prospective randomized trial American Surgeon. ,vol. 57, pp. 618- 623 ,(1991)
D. Sharp, A. J. Williams, R. A. Banks, C. A. M. Mcnulty, I. D. Dittmer, A prospective study of central venous hemodialysis catheter colonization and peripheral bacteremia. Clinical Nephrology. ,vol. 51, pp. 34- 39 ,(1999)
K.M. Chow, C.C. Szeto, C.B. Leung, T. Y.H. Wong, P.K.T. Li, Cuffed-tunneled femoral catheter for long-term hemodialysis. International Journal of Artificial Organs. ,vol. 24, pp. 443- 446 ,(2001) , 10.1177/039139880102400702
Naomi P O'Grady, Mary Alexander, E Patchen Dellinger, Julie L Gerberding, Stephen O Heard, Dennis G Maki, Henry Masur, Rita D McCormick, Leonard A Mermel, Michele L Pearson, Issam I. Raad, Adrienne Randolph, Robert A Weinstein, None, Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. ,vol. 51, pp. 1- 29 ,(2002)
John E. Moran, Subcutaneous vascular access devices. Seminars in Dialysis. ,vol. 14, pp. 452- 457 ,(2001) , 10.1046/J.1525-139X.2001.00111.X
B Hoen, M Kessler, A Paul-Dauphin, D Hestin, EPIBACDIAL: a multicenter prospective study of risk factors for bacteremia in chronic hemodialysis patients. Journal of The American Society of Nephrology. ,vol. 9, pp. 869- 876 ,(1998) , 10.1681/ASN.V95869