The added challenges of bone metastases treatment in elderly patients.

作者: L. Zeng , E. Chow

DOI: 10.1016/J.CLON.2012.11.001

关键词:

摘要: Most cancers occur in those older than the age of 65 years. As population world ages and life expectancies continue to increase, it is important address treatment challenges for elderly patients. This narrative review details palliative radiotherapy patients with bone metastases. We begin definition its appropriateness, outlining recent demographic data cancer. The current status participation clinical trials discussed by reviewing literature trial data. Factors affecting enrolment are assessed, a focus on trials, what we can do improve accrual this data-driven setting. At present, there lack level 1 evidence that evaluates optimal Therefore, safety efficacy given based previously published reports. Palliative worthwhile should be recommended regardless age, as supported available evidence. Patient, family physician concerns about physical burden may reduced single treatments (that often done visit) beneficial multiple painful In patients, even best these cases opioid-related adverse events amplified group dosages more difficult titrate. Clinicians encourage form basis guidelines. Radiation oncologists encouraged reduce offering where appropriate completing consultation, simulation visit.

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