Early human experience with per-oral endoscopic pyloromyotomy (POP).

摘要: Gastroparesis is a condition characterized by delayed gastric emptying, and constellation of symptoms, including nausea, vomiting, early satiety, bloating. Although current surgical options such as pyloroplasty have been shown to be effective, an endoscopic submucosal myotomy technique may applied divide the pyloric sphincter without access. Such provide benefits natural orifice procedure, improve emptying in gastroparetic patients. Per-oral pyloromyotomy (POP) was performed seven female patients aged 33–65 years (mean 51 years). All had pre-operative work-up that included upper endoscopy, and study. A pH study, esophageal manometry were also when concomitant fundoplication considered. POP technically successful all cases. There were no immediate procedural complications. Perioperative, complications included: one patient with GI bleed 2 weeks post-procedure, necessitating transfusions, clipping channel ulcer; who experienced difficulty swallowing post operatively, delaying discharge 1 day; developed hospital-acquired pneumonia, several days. Six significant symptomatic improvement following procedure. Three month follow-up nuclear medicine solid-phase studies are currently available for 5 7 Normal at 4 h noted four five (80 %). One did not respond management subsequently underwent uneventful laparoscopic pyloroplasty, which failed significantly her symptoms. safe feasible Early suggests promising well objective emptying. Additional clinical experience required establish role this gastroparesis.