Molecular structure, biology, and genetics of prions.
作者： Stanley B. Prusiner
DOI: 10.1016/S0065-3527(08)60709-5
关键词:
摘要: Publisher Summary One of the most fascinating and perplexing areas current biomedical research concerns structure biology unusual infectious particles causing scrapie in animals Creutzfeldt-Jakob disease (CJD) humans. Over last few years considerable progress has been made unraveling some mysteries surrounding these novel pathogens designated prions. Kuru, CJD, Gerstmann-Straussler syndrome (GSS) are all transmissible neurodegenerative diseases The transmissibility three to experimental greatly facilitated studies concerning their etiology pathogenesis. Like kuru GSS also appear be caused by Three apparently prions: sheep goats, mink encephalopathy (TME), chronic wasting (CWD) mule deer elk.
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