Screening and diagnostic modalities in carcinoma cervix: A Pathologist's perspective.

摘要: Carcinoma cervix is the second most common cancer among women worldwide with majority of cases in developing nations. It develops over a considerable period time through precursor lesions that are amenable to detection when properly screened. A sea change has occurred and further management cervical advances field diagnostics. The orchestra ranges from conventional Papanicolaou (Pap) test high throughout expression profiling. discovery human papilloma virus (HPV) as etiologic agent recognition various risk types prompted development techniques for HPV detection. Several biomarkers have been recognized although many them still require validation before they can be put use at large scale. Efforts directed early carcinoma desired reducing incidence rates cervix. This review highlights screening guidelines entire available armamentarium which applied screen diagnose an stage. However it foreseen etiology based testing unlikely replace cytology modality will remain useful adjunct. especially true countries resource poor where cost-effective Pap continues main method.