Reappraisal of metastatic lymph node topography in head and neck squamous cell carcinomas
作者： Lei Tao , Marine Lefèvre , Patrice Callard , Sophie Périé , Jean-François Bernaudin
DOI: 10.1016/J.OTOHNS.2006.02.010
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摘要: Objective To analyze the lymphatic distribution of metastatic carcinomatous cells in cervical lymph nodes head and neck squamous cell carcinoma (HNSCC). Study design setting We retrospectively reviewed 119 patients treated our hospital for HNSCC (1999-2004). Topography dissection specimens was prospectively classified according to classification Robbins. The 4000 were analyzed by optical microscopy using hematoxylin-eosin-safran (HES) staining. In cases negative results level II, cytokeratin (AE1/AE3) immunodetection performed. Results Metastases visualized HES 6.4% oral cavity, 4.7% oropharyngeal, 4.4% hypopharyngeal, 1.3% endolaryngeal cancers. highest incidence nodal metastasis observed IIa (P Conclusions Level is main involved regional metastases HNSCC, regardless primary site cancer. However, eight (6.7%) patients, II spared, as confirmed IHC. these cases, did not represent first step drainage from tumor. sentinel node technique discussed light results.
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