Expression of bcl-2 in salivary glands and salivary gland adenomas. A contribution to the reserve cell theory.
作者： J. Pammer , R. Horvat , W. Weninger , W. Ulrich
DOI: 10.1016/S0344-0338(11)80920-9
关键词:
摘要: Summary The bcl-2 proto-oncogene product inhibits apoptosis. It has been suggested that assists the survival of stem cells. Bcl-2 also plays a role in development adenomas. In salivary glands it is expressed basal cells striated and excretory ducts which may indicate these are reserve Acinar cells, myoepithelial most luminal negative for bcl-2. cell adenomas Warthin#X2019:s tumors found predominantly with differentiation. pleomorphic mainly tubulo-ductal structures, at various degrees patterns solid trabecular areas low degree myxoid areas. chondroid adenomas, myoepitheliomas oncocytomas only focally or missing. If inhibition apoptosis significant genesis neoplasms, then factors other than must be effective.
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sci-hub.se 参考文章(19)
Shawn M. Brisbay, Timothy J. McDonnell, Patricia Troncoso, Leland W. K. Chung, Martin L. Campbell, Jer-Tsong Hsieh, Shi-Ming Tu, Christopher Logothetis, Expression of the Protooncogene bcl-2 in the Prostate and Its Association with Emergence of Androgen-independent Prostate Cancer Cancer Research. ,vol. 52, pp. 6940- 6944 ,(1992)
Dominique Chopin, Ralph Buttyan, Mitchell Benson, Carl A. Olsson, Sixtina Gil, Stanley Korsmeyer, Kathleen M. O'Toole, Fraser Symmans, Marc Colombel, Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers. American Journal of Pathology. ,vol. 143, pp. 390- 400 ,(1993)
John Minna, Yoshihide Tsujimoto, Makoto Katsumata, Naohiko Ikegaki, Expression of bcl-2 in Small Cell Lung Carcinoma Cells Cancer Research. ,vol. 54, pp. 6- 8 ,(1994)
D. M. Hockenbery, M. Zutter, W. Hickey, M. Nahm, S. J. Korsmeyer, BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 6961- 6965 ,(1991) , 10.1073/PNAS.88.16.6961
Francesco Pezzella, Helen Turley, Isinzu Kuzu, Mohammed Fahim Tungekar, Michael S. Dunnill, Chris B. Pierce, Adrian Harris, Kevin C. Gatter, David Y. Mason, bcl-2 Protein in Non-Small-Cell Lung Carcinoma The New England Journal of Medicine. ,vol. 329, pp. 690- 694 ,(1993) , 10.1056/NEJM199309023291003
Irving Dardick, Roger W. Byard, Jacqueline A. Carnegie, A review of the proliferative capacity of major salivary glands and the relationship to current concepts of neoplasia in salivary glands. Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 69, pp. 53- 67 ,(1990) , 10.1016/0030-4220(90)90269-X
Qi-Long Lu, Richard Poulsom, Leslie Wong, Andrew M. Hanby, Bcl-2 expression in adult and embryonic non-haematopoietic tissues. The Journal of Pathology. ,vol. 169, pp. 431- 437 ,(1993) , 10.1002/PATH.1711690408
Richard M. Palmer, Raleigh B. Lucas, Jennifer Knight, Barry Gusterson, Immunocytochemical identification of cell types in pleomorphic adenoma, with particular reference to myoepithelial cells The Journal of Pathology. ,vol. 146, pp. 213- 220 ,(1985) , 10.1002/PATH.1711460308
B. F. Burns, I. Dardick, W. R. Parks, Intermediate filament expression in normal parotid glands and pleomorphic adenomas. Virchows Archiv. ,vol. 413, pp. 103- 112 ,(1988) , 10.1007/BF00749671
Stephen B. Williams, Gary L. Ellis, Paul L. Auclair, Immunohistochemical analysis of basal cell adenocarcinoma Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 75, pp. 64- 69 ,(1993) , 10.1016/0030-4220(93)90408-V