Febrile seizures and mesial temporal sclerosis: No association in a long-term follow-up study.

作者: R. Tarkka , E. Paakko , J. Pyhtinen , M. Uhari , H. Rantala

DOI: 10.1212/01.WNL.0000037482.55894.B1

关键词:

摘要: Objective: To determine whether febrile seizures cause mesial temporal sclerosis (MTS), the occurrence of MTS was evaluated in an unselected series patients with seizures. Methods: Twenty-four a prolonged first seizure, 8 unprovoked seizure after and 32 age-, sex-, handedness-matched control subjects single simple without later were selected from 329 followed up prospectively. The mean follow-up time 12.3 years by MR volumetry amygdala hippocampal formation qualitative analysis structures. Results: None had MTS. total volumes right left formations did not differ significantly between any three groups. revealed no sclerotic changes area. initial lower right–left volume difference than subjects, but this effect on outcome. Conclusion: following even is uncommon event, confirming good clinical outcome

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