Optic disc edema in non-arteritic anterior ischemic optic neuropathy.

摘要: We investigated the clinical characteristics, time to resolution and factors that influence it, evolutionary pattern of optic disc edema (ODE) in non-arteritic anterior ischemic neuropathy (NA-AION). Our study was conducted 591 consecutive patients (749 eyes) with NA-AION who fulfilled our inclusion criteria. On their first visit clinic, all had a detailed ophthalmic medical history, comprehensive evaluation, stereoscopic color fundus photography fluorescein angiography. each follow-up visit, same evaluation performed, except for The effect steroid therapy on ODE evaluated “patient choice study” 723 eyes, i.e., voluntarily opted have (343 or not (380 this therapy. To identify resolution, parametric regression models interval-censored data were fitted by maximum likelihood estimation using an SAS procedure. results indicate overall median (25–75th percentile) spontaneous from onset visual loss 7.9 (5.8–11.4) weeks. longer diabetics than non-diabetics (p = 0.003) single factor model. Multi-factor analysis showed worse initial field defects < 0.0001) acuity 0.04) associated faster ODE. Those treated within 2 weeks after significantly 0.0006) untreated cases. Severity systemic diseases identical patients. A characteristic observed. In conclusion, course is shorter greater severity loss, which may relate number axons permanently damaged during acute stage. Steroid Resolution goes through process.