Seasonal variation of enteric infections and inflammatory bowel disease.

作者: Amnon Sonnenberg

DOI: 10.1002/IBD.20408

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摘要: Background: The time trends of inflammatory bowel disease are characterized by short-term variations that affect Crohn's and ulcerative colitis alike. aim the present study was to test whether these might be related exacerbations secondary superimposed gastrointestinal infection. Methods: Hospital Episode Statistics (HES) comprises a data set all patients admitted hospitals throughout England, which includes inpatients day cases. This used analyze monthly in hospital admissions for (ICD10 code K50), (K51), bacterial intestinal infections (A04), viral (A08), diarrhea infectious gastroenteritis (A09), upper respiratory (J06), pneumonia unspecified organism (J18), acute lower infection (J22). Results: temporal analysis revealed similar fluctuations disease, colitis, infections. Viral were different seasonal showed no relationship with any or Similarly, resulted marked cyclical unrelated changes enteric infections. Conclusions: similarity suggests superinfection bacteria responsible disease. (Inflamm Bowel Dis 2008)

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