Dispositional Optimism and All-Cause and Cardiovascular Mortality in a Prospective Cohort of Elderly Dutch Men and Women

摘要: Background Major depression is known to be related higher cardiovascular mortality. However, epidemiological data regarding dispositional optimism in relation mortality are scanty. Objective To test whether subjects who optimistic live longer than those pessimistic. Design Our analysis formed part of a prospective population-based cohort study the Netherlands (Arnhem Elderly Study). Setting General community. Participants aged 65 85 years (999 men and women) completed 30-item validated Dutch Scale Subjective Well-being for Older Persons, with 5 subscales: health, self-respect, morale, optimism, contacts. A total 941 (466 475 had complete data, these were divided into quartiles. Main Outcome Measure Number deaths during follow-up period. Results During period 9.1 (1991-2001), there 397 deaths. Compared high level pessimism, reporting an age- sex-adjusted hazard ratio 0.55 (95% confidence interval, 0.42-0.74; upper vs lower quartile) all-cause For mortality, was 0.23 0.10-0.55) when adjusted age, sex, chronic disease, education, smoking, alcohol consumption, history disease or hypertension, body mass index, cholesterol level. Protective trend relationships observed between ( P  = .001 trend, respectively). Interaction sex  = .04) supported stronger protective effect women but not Conclusions results provide support graded independent relationship old age. Prevention accounted much effect.