Surgical Resection for Melanoma Metastatic to the Gastrointestinal Tract

摘要: Objective: To evaluate the role of surgery in survival patients with melanoma metastatic to gastrointestinal (GI) tract. Design: Retrospective review. Setting: Tertiary cancer center. Patients: One hundred twenty-four potential surgical candidates stomach, small intestine, colon, or rectum. Main Outcome Measures: Operative morbidity and mortality, relief presenting symptoms, median 5-year survival. Results: The disease-free interval prior diagnosis GI tract metastasis was 23.2 months (range, 1-154 months). Patients typically presented crampy abdominal pain, symptomatic mass, and/or occult blood loss. Of 124 patients, 69 (55%) underwent exploration abdomen, 46 (66%) had curative resection, 23 (34%) a palliative procedure. There only 1 operative death major complication; 67 (97%) experienced postoperative their symptoms. undergoing resection 48.9 months, compared 5.4 5.7 those procedures nonsurgical interventions, respectively. By multivariate analysis, 2 most important prognostic factors for long-term were complete metastases as initial site distant metastases. Conclusions: Almost all can have palliation symptoms by intervention minimal mortality. high rate associated indicates that should be strongly considered this subgroup disease. Arch Surg. 1996;131:975-980