Bacteriological studies of blood, tissue fluid, lymph and lymph nodes in patients with acute dermatolymphangioadenitis (DLA) in course of 'filarial' lymphedema.

摘要: Filarial lymphedema is complicated by frequent episodes of dermatolymphangioadenitis (DLA). Severe systemic symptoms during attacks DLA resemble those septicemia. The question we asked was whether bacterial isolates can be found in the peripheral blood patients DLA. Out 100 referred to us with 'filarial' 14 displayed acute and five subacute All were on admission microfilariae negative but had a positive test past. Blood nine cases, four (21%) (26%). In 10 cases cultures negative. Six belonged Bacilli, Cocci one Sarcina. To identify sites origin dissemination, swabs taken from calf skin biopsy wounds tissue fluid, lymph node specimens cultured. Swabs wound contained (47%) cases. They Bacilli nine, three, Acinetobacter Erwinia two Tissue fluid collected (40%) Staphylococci three (30%). Lymph drained all samples (100%). Staphylococcus epidermis, xylosus aureus, Acinetobacter, Bacillus subtilis Three nodes biopsied chromogenes, xylosus, Enterococcus cereus. six same phenotypically defined species bacteria limb tissues or fluids. 'control' group without changes Interestingly, these 80%, 68%, 70% 58% healthy controls, did not contain bacteria, only 12% This study demonstrates that reveal bacteremia high percentage Diversity points breakdown immune barrier subsequently indiscriminate colonization deep spread an circulation.