Unstable DNA amplifications in methotrexate resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization

作者: Stephen M. Beverley , Jeffrey A. Coderre , Daniel V. Santi , Robert T. Schimke

DOI: 10.1016/0092-8674(84)90498-7

关键词:

摘要: … The cell lines utrlized were the initially selected RIOOO-3 lrne (revived from frozen storage) (a), or this same line grown an additional eight months in 1 mM MTX, the RIOOO11 line (b). …

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