Structure of amplified DNA in different Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate.

作者: F Ardeshir , E Giulotto , J Zieg , O Brison , W S Liao

DOI: 10.1128/MCB.3.11.2076

关键词: MutantDNABiologygenomic DNAGeneticsAmplified fragment length polymorphismNucleic acid thermodynamicsRestriction fragmentGeneMolecular biologyMolecular cloning

摘要: Syrian hamster cell lines selected in multiple steps for resistance to high levels of N-(phosphonacetyl)-L-aspartate (PALA) contain many copies of the gene coding for the pyrimidine …

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