Les souris ne sont pas des hommes et pourtant…
作者： Anne Cachat , Julien Villaudy , Dominique Rigal , Louis Gazzolo , Madeleine Duc Dodon
DOI: 10.1051/MEDSCI/2012281018
关键词:
摘要: L’etude des pathologies humaines est souvent limitee par l’absence de modele animal approprie. La souris le plus frequemment utilise pour l’etude maladies infectieuses humaines. Cependant, un grand nombre d’agents infectieux specifiques l’homme n’infectent pas la souris. Ces vingt dernieres annees, greffe cellules progenitrices ou tissus humains chez immunodeficientes a permis generer dites humanisees. Bien que ces modeles demandent encore etre ameliores, ils ont reproduire certains aspects et laissent ainsi esperer developpement dans futur proche therapies innovantes.
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