Coronary artery calcifications in the long-term follow-up of Kawasaki disease

摘要: Background To determine if detection of coronary artery calcifications in patients with Kawasaki disease may serve as a noninvasive predictor future events. Methods A prospective, cohort pilot study that included 18 >1 year from the acute was performed including 9 abnormalities during illness (Group 1) and without 2). Patients were classified by echocardiography having none, resolved, or residual abnormalities. Electron beam computed tomography (EBCT) scans completed using Agatson calcium scoring system. Intermediate follow-up 2.5 years after EBCT to clinically significant events (myocardial infarction sudden death) had occurred. Results Late echocardiographic corresponded early 5 (P = .029) Group 1. The late significantly correlated 4 (95% CI 28%-99%). One patient highest score subsequently death. Detection be predictive death .056). No abnormalities, calcifications, occurred 2 patients. Conclusions show evidence calcifications. useful for risk stratification long-term management disease.