Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemia.

作者: S. Mittnacht , J. L. Farber , K. R. Chien

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摘要: … Ischemia Studies in our laboratory over the last 4 years using in situ liver and myocardial ischemia … the mitochondrion in the irreversibility of ischemic cell injury and have reached some …

参考文章(83)
J. L. Farber, R. G. Pfau, F. A. X. Schanne, Galactosamine-induced cell death in primary cultures of rat hepatocytes. American Journal of Pathology. ,vol. 100, pp. 25- 38 ,(1980)
R. S. Decker, A. R. Poole, J. S. Crie, J. T. Dingle, K. Wildenthal, Lysosomal alterations in hypoxic and reoxygenated hearts. II. Immunohistochemical and biochemical changes in cathepsin D. American Journal of Pathology. ,vol. 98, pp. 445- 455 ,(1980)
C. A. Halverson, M. Ashraf, Structural changes in the freeze-fractured sarcolemma of ischemic myocardium. American Journal of Pathology. ,vol. 88, pp. 583- 594 ,(1977)
R.J. Adams, D.W. Cohen, S. Gupte, J.D. Johnson, E.T. Wallick, T. Wang, A. Schwartz, In vitro effects of palmitylcarnitine on cardiac plasma membrane Na,K-ATPase, and sarcoplasmic reticulum Ca2+-ATPase and Ca2+ transport. Journal of Biological Chemistry. ,vol. 254, pp. 12404- 12410 ,(1979) , 10.1016/S0021-9258(19)86329-9
K. R. Chien, J. T. Martin, J. L. Farber, Irreversible ischemic cell injury. Prevention by chlorpromazine of the aggregation of the intramembranous particles of rat liver plasma membranes. American Journal of Pathology. ,vol. 92, pp. 713- 732 ,(1978)
Robert A. Haworth, Douglas R. Hunter, The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site. Archives of Biochemistry and Biophysics. ,vol. 195, pp. 460- 467 ,(1979) , 10.1016/0003-9861(79)90372-2
D.R. Pfeiffer, P.C. Schmid, M.C. Beatrice, H.H. Schmid, Intramitochondrial phospholipase activity and the effects of Ca2+ plus N-ethylmaleimide on mitochondrial function. Journal of Biological Chemistry. ,vol. 254, pp. 11485- 11494 ,(1979) , 10.1016/S0021-9258(19)86511-0
Douglas R. Hunter, Robert A. Haworth, The Ca2+-induced membrane transition in mitochondria. III. Transitional Ca2+ release. Archives of Biochemistry and Biophysics. ,vol. 195, pp. 468- 477 ,(1979) , 10.1016/0003-9861(79)90373-4
D R Hunter, R A Haworth, J H Southard, Relationship between configuration, function, and permeability in calcium-treated mitochondria. Journal of Biological Chemistry. ,vol. 251, pp. 5069- 5077 ,(1976) , 10.1016/S0021-9258(17)33220-9