MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells
作者： Ziqiang Zhu , Jinshan Tang , Jianqiang Wang , Gang Duan , Lei Zhou
DOI: 10.1371/JOURNAL.PONE.0150026
关键词:
摘要: … Third, we found that EZH2 was a direct target of miR-138 and that forced EZH2 expression … enhances osteosarcoma cell chemosensitivity to cisplatin by targeting EZH2. In conclusion, …
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Wen Zhou, Jian Wang, Wang-Ying Man, Qing-Wei Zhang, Wen-Gui Xu, siRNA silencing EZH2 reverses cisplatin-resistance of human non-small cell lung and gastric cancer cells. Asian Pacific Journal of Cancer Prevention. ,vol. 16, pp. 2425- 2430 ,(2015) , 10.7314/APJCP.2015.16.6.2425
Juan Xu, Li Li, Hui-fang Yun, Ye-shan Han, MiR-138 promotes smooth muscle cells proliferation and migration in db/db mice through down-regulation of SIRT1. Biochemical and Biophysical Research Communications. ,vol. 463, pp. 1159- 1164 ,(2015) , 10.1016/J.BBRC.2015.06.076
Zhiming Wu, Huangen Wang, Sunyang Fang, Chaoyang Xu, MiR-449c inhibits gastric carcinoma growth. Life Sciences. ,vol. 137, pp. 14- 19 ,(2015) , 10.1016/J.LFS.2015.06.020
Xian-wei Ye, Hong Yu, Yan-kun Jin, Xiao-ting Jing, Mei Xu, Zi-fen Wan, Xiang-yan Zhang, miR-138 inhibits proliferation by targeting 3-phosphoinositide-dependent protein kinase-1 in non-small cell lung cancer cells The Clinical Respiratory Journal. ,vol. 9, pp. 27- 33 ,(2015) , 10.1111/CRJ.12100
Fei Ma, Mingdi Zhang, Wei Gong, Mingzhe Weng, Zhiwei Quan, MiR-138 Suppresses Cell Proliferation by Targeting Bag-1 in Gallbladder Carcinoma. PLOS ONE. ,vol. 10, ,(2015) , 10.1371/JOURNAL.PONE.0126499
A. Grilli, M. Sciandra, M. Terracciano, P. Picci, K. Scotlandi, Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model BMC Medical Genomics. ,vol. 8, pp. 34- 34 ,(2015) , 10.1186/S12920-015-0106-0
Naiara Martinez-Velez, Enric Xipell, Patricia Jauregui, Marta Zalacain, Lucía Marrodan, Carolina Zandueta, Beatriz Vera, Leire Urquiza, Luis Sierrasesúmaga, Mikel San Julián, Gemma Toledo, Juan Fueyo, Candelaria Gomez-Manzano, Wensceslao Torre, Fernando Lecanda, Ana Patiño-García, Marta M Alonso, The oncolytic adenovirus Δ24-RGD in combination with cisplatin exerts a potent anti-osteosarcoma activity. Journal of Bone and Mineral Research. ,vol. 29, pp. 2287- 2296 ,(2014) , 10.1002/JBMR.2253
MULIANG DING, JIANZHONG HU, JIANGDONG NI, ZHONGHUI ZHENG, DEYE SONG, JUNJIE WANG, Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells Oncology Letters. ,vol. 9, pp. 2261- 2267 ,(2015) , 10.3892/OL.2015.3036
Lisa Mirabello, Rebecca J. Troisi, Sharon A. Savage, Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program Cancer. ,vol. 115, pp. 1531- 1543 ,(2009) , 10.1002/CNCR.24121
Meng Xu, Hua Jin, Cheng-Xiong Xu, Wen-Zhi Bi, Yan Wang, MiR-34c inhibits osteosarcoma metastasis and chemoresistance. Medical Oncology. ,vol. 31, pp. 972- 972 ,(2014) , 10.1007/S12032-014-0972-X