摘要: Recent advances of medaka bone development are described, which include osteoblast- and osteoclast-specific cells marker genes, by using new techniques: screening fin ray mutants followed positional cloning, transgenic lines employing osteoblast osteoclast specific promoters linked with a fluorescent protein, in addition to electron microscopy for histology. Because live imaging becomes the most powerful tool characterization cell organ formation, studies as an animal model bring molecular cellular insights visual data from line specifically derived coupling mutant.
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