Deep brain stimulation for dystonia-choreoathetosis in cerebral palsy: Pallidal versus thalamic stimulation.

摘要: Abstract Introduction Dystonia-choreoathetosis is common in patients with cerebral palsy, and medical treatment mostly unsatisfactory. Deep brain stimulation (DBS) of the globus pallidus internus (GPi) has shown some effect, but there still a need to optimize strategies. We aimed assess whether thalamic ventral intermediate nucleus (Vim) might be an alternative DBS target dystonia-choreoathetosis. Methods Three palsy dystonia-choreoathetosis underwent implantation electrodes concurrently GPi Vim. Final selection site switches during follow-up corresponding clinical outcomes were assessed. Results One patient initial was switched Vim, likewise did not improve significantly (BFM: pre-OP 142, 140, Vim 134) discontinued. In one chosen as for chronic DBS. Since benefit yet satisfying, resulting further mild improvement 99.5, 82.5, 82). selected kept on due therapeutic effect 135, 121). Conclusions The represents most convenient show relevant long-term advantage everyday life our patients. Further targets considered acquired dystonia.