Ribonucleotide reductase subunit one as gene therapy target: commentary re: M-Y. Cao et al., Adenovirus-mediated ribonucleotide reductase R1 gene therapy of human colon adenocarcinoma. Clin. Cancer Res., 9: 4304-4308, 2003.
作者： Yun Yen
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摘要: RNR[2][1] catalyzes the reaction in which 2′-deoxyribonucleotides are generated from corresponding ribonucleotide 5′-diphosphates. This is rate-limiting step production of 2′-deoxyribonucleoside 5′-triphosphates required for DNA replication. RNR consists two protein
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