Scalable Production and Isolation of Extracellular Vesicles: Available Sources and Lessons from Current Industrial Bioprocesses.

作者: Carolina Paganini , Umberto Capasso Palmiero , Gabriella Pocsfalvi , Nicolas Touzet , Antonella Bongiovanni

DOI: 10.1002/BIOT.201800528

关键词:

摘要: … In this review, possible directions toward the scalable production of EVs are discussed. In particular, two strategies are considered: i) the optimization of upstream unit operations and ii) …

参考文章(115)
Weihong Qu, Mingxi Wang, Yaqing Wu, Ruian Xu, Scalable Downstream Strategies for Purification of Recombinant Adeno- Associated Virus Vectors in Light of the Properties Current Pharmaceutical Biotechnology. ,vol. 16, pp. 684- 695 ,(2015) , 10.2174/1389201016666150505122228
Stefania Raimondo, Flores Naselli, Simona Fontana, Francesca Monteleone, Alessia Lo Dico, Laura Saieva, Giovanni Zito, Anna Flugy, Mauro Manno, Maria Antonietta Di Bella, Giacomo De Leo, Riccardo Alessandro, Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death Oncotarget. ,vol. 6, pp. 19514- 19527 ,(2015) , 10.18632/ONCOTARGET.4004
Paola Gagni, Marina Cretich, Luisa Benussi, Elisa Tonoli, Miriam Ciani, Roberta Ghidoni, Benedetta Santini, Elisabetta Galbiati, Davide Prosperi, Marcella Chiari, Combined mass quantitation and phenotyping of intact extracellular vesicles by a microarray platform. Analytica Chimica Acta. ,vol. 902, pp. 160- 167 ,(2016) , 10.1016/J.ACA.2015.10.017
Leonora Balaj, Nadia A. Atai, Weilin Chen, Dakai Mu, Bakhos A. Tannous, Xandra O. Breakefield, Johan Skog, Casey A. Maguire, Heparin affinity purification of extracellular vesicles. Scientific Reports. ,vol. 5, pp. 10266- 10266 ,(2015) , 10.1038/SREP10266
Yunmi Jeon, Myung Sook Lee, Yong-Pil Cheon, Decreased Contact Inhibition in Mouse Adipose Mesenchymal Stem Cells Development & reproduction. ,vol. 16, pp. 329- 338 ,(2012) , 10.12717/DR.2012.16.4.329
Ákos M. Lőrincz, Csaba I. Timár, Krisztina A. Marosvári, Dániel S. Veres, Lilla Otrokocsi, Ágnes Kittel, Erzsébet Ligeti, Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytes Journal of extracellular vesicles. ,vol. 3, pp. 25465- 25465 ,(2014) , 10.3402/JEV.V3.25465
Emily Zeringer, Timothy Barta, Mu Li, Alexander V. Vlassov, Strategies for isolation of exosomes. CSH Protocols. ,vol. 2015, pp. 319- 323 ,(2015) , 10.1101/PDB.TOP074476