Vitamin D and maternal and child health: Overview and implications for dietary requirements

摘要: The essentiality of vitamin D for normal growth and development has been recognized over 80 years, fortification programs have in place the United States more than 70 years. Despite above, deficiency continues to be a common finding certain population groups. Vitamin suggested as potential risk factor preeclampsia, during infancy early childhood is associated with an increased numerous skeletal disorders, well immunological vascular abnormalities. can occur through multiple mechanisms including consumption diets low this inadequate exposure environmental ultraviolet B rays. value supplementation high-risk pregnancies discussed. Currently, there vigorous debate concerning what constitutes appropriate intakes exemplified by differing recommendations from Institute Medicine Dietary Reference Intake report recent Endocrine Society. As discussed, major issue that needs resolved key biological endpoint should used when making pregnant woman her offspring. Birth Defects Research (Part C) 99:24–44, 2013. © 2013 Wiley Periodicals, Inc.