Cerebellar and Spinal tDCS

作者: Roberta Ferrucci , Tommaso Bocci , Alberto Priori

DOI: 10.1007/978-3-319-33967-2_12

关键词:

摘要: In the last 5–7 years, cerebellar and spinal DC stimulation received growing attention by experimental clinical neuroscientists. Although efficacy of tDCS awaits confirmation in large, clinical, randomized controlled studies, there are now several important key points underlying their mechanisms action that should be discussed. Briefly, delivering currents for few minutes over cerebellum or cord can induce persistent, polarity-dependent excitability changes persisting after current offset. Cerebellar elicit neurophysiological behavioral both motor functions cognitive-behavioral domain. Spinal elicits related to functions, but, interestingly, also brain may arise from activation tonic afferent systems brain. Future studies endeavor assess whether data translate into benefits real life, lengthen benefits, investigate how changing variables influences tDCS-induced effects, determine possible interactions with other treatments, improve patients’ selection.

参考文章(53)
Daniel Meron, Nicholas Hedger, Matthew Garner, David S. Baldwin, Transcranial direct current stimulation (tDCS) in the treatment of depression: Systematic review and meta-analysis of efficacy and tolerability Neuroscience & Biobehavioral Reviews. ,vol. 57, pp. 46- 62 ,(2015) , 10.1016/J.NEUBIOREV.2015.07.012
Tommaso Bocci, Matteo Caleo, Beatrice Vannini, Maurizio Vergari, Filippo Cogiamanian, Simone Rossi, Alberto Priori, Ferdinando Sartucci, An unexpected target of spinal direct current stimulation: Interhemispheric connectivity in humans. Journal of Neuroscience Methods. ,vol. 254, pp. 18- 26 ,(2015) , 10.1016/J.JNEUMETH.2015.07.012
Gabriel Tortella, Roberta Casati, Luana VM Aparicio, Antonio Mantovani, Natasha Senço, Giordano D’Urso, Jerome Brunelin, Fabiana Guarienti, Priscila Mara Lorencini Selingardi, Débora Muszkat, Bernardo de Sampaio Pereira Junior, Leandro Valiengo, Adriano H Moffa, Marcel Simis, Lucas Borrione, André R Brunoni, None, Transcranial direct current stimulation in psychiatric disorders. World journal of psychiatry. ,vol. 5, pp. 88- 102 ,(2015) , 10.5498/WJP.V5.I1.88
D. L. Voisin, N. Guy, M. Chalus, R. Dallel, Nociceptive stimulation activates locus coeruleus neurones projecting to the somatosensory thalamus in the rat The Journal of Physiology. ,vol. 566, pp. 929- 937 ,(2005) , 10.1113/JPHYSIOL.2005.086520
Francesco Saverio Bersani, Amedeo Minichino, Laura Bernabei, Francesco Spagnoli, Lucilla Vergnani, Alessandra Corrado, Ines Taddei Ines, Massimo Biondi, Roberto Delle Chiaie, Prefronto–cerebellar transcranial direct current stimulation improves visuospatial memory, executive functions, and neurological soft signs in patients with euthymic bipolar disorder Neuropsychiatric Disease and Treatment. ,vol. 11, pp. 2265- 2270 ,(2015) , 10.2147/NDT.S79108
J. Aguilar, F. Pulecchi, R. Dilena, A. Oliviero, A. Priori, G. Foffani, Spinal direct current stimulation modulates the activity of gracile nucleus and primary somatosensory cortex in anaesthetized rats. The Journal of Physiology. ,vol. 589, pp. 4981- 4996 ,(2011) , 10.1113/JPHYSIOL.2011.214189
Joseph R. Phillips, Doaa H. Hewedi, Abeer M. Eissa, Ahmed A. Moustafa, The cerebellum and psychiatric disorders. Frontiers in Public Health. ,vol. 3, pp. 66- 66 ,(2015) , 10.3389/FPUBH.2015.00066
Remy Bation, Emmanuel Poulet, Frederic Haesebaert, Mohamed Saoud, Jerome Brunelin, Transcranial direct current stimulation in treatment-resistant obsessive-compulsive disorder: An open-label pilot study. Progress in Neuro-psychopharmacology & Biological Psychiatry. ,vol. 65, pp. 153- 157 ,(2016) , 10.1016/J.PNPBP.2015.10.001
A. Truini, M. Vergari, A. Biasiotta, S. La Cesa, M. Gabriele, G. Di Stefano, C. Cambieri, G. Cruccu, M. Inghilleri, A. Priori, Transcutaneous spinal direct current stimulation inhibits nociceptive spinal pathway conduction and increases pain tolerance in humans. European Journal of Pain. ,vol. 15, pp. 1023- 1027 ,(2011) , 10.1016/J.EJPAIN.2011.04.009