Impact of the atherosclerotic process in patients with diabetes.

摘要: Between 120 and 140 million people suffer from diabetes mellitus (type 1 type 2) worldwide, this number may well double by the year 2025. Patients with are at increased risk of atherosclerosis its clinical sequelae: coronary, peripheral vascular, cerebrovascular diseases. Concurrently, most common cause death in persons is myocardial infarction. The pathogenesis, progression, epidemiology atherosclerotic disease distinct patients diabetes. Atherosclerosis can develop much earlier life, an accelerated rate, compared non-diabetic individuals. One factors responsible for related to atherogenic lipid profile pathobiological processes that transforming dormant plaques into active rupture-prone be enhanced as well. It follows a major challenge treatment reduce disease. third National Cholesterol Education Program (NCEP) report recently recommended management dyslipidaemia should aggressive those established coronary heart (CHD). NCEP Adult Treatment Panel III guidelines recommend statins elevated CHD.