Functional interactions of 2-phenylethylamine and of tryptamine with brain catecholamines: implications for psychotherapeutic drug action.
DOI: 10.1016/0278-5846(89)90131-0
关键词:
摘要: Abstract 1. The relevance of trace amine research is outlined for PEA and T in the context Psychotherapeutic drug action, particularly relation to actions MAO-inhibitor antidepressant drugs. 2. Evidence neuronal localization these amines their relationship brain catecholamines discussed with respect possible co-localization DA distribution within nigro-striatal/striato-nigral system. 3. results recent experiments assessing behavioural effects prodrugs are described. interactions compounds MAO inhibitors assessed systems. 4. Recent evidence functional decreases β-adrenergic receptors following chronic administration outlined. lack association such percentage inhibition observed after treatments indicates influences (or metabolites) on factors other than activity as mediators effects. role (as a metabolite PLZ) this proposed. involvement emergent changes Induced by drugs hypothesized ongoing research.
sci-hub.se 参考文章(43)
Alan A. Boulton, Augusto V. Juorio, Brain Trace Amines Springer, Boston, MA. pp. 189- 222 ,(1982) , 10.1007/978-1-4757-0614-7_8
Salomon Z. Langer, Sonia Arbilla, Ruth Niddam, Sanàa Benkirane, Patrice Baud, Pharmacological Profile of β-Phenylethylamine on Dopaminergic and Noradrenergic Neurotransmission in Rat Cerebral Slices : Comparison with Amphetamine and Other Trace Amines Humana Press. pp. 27- 38 ,(1985) , 10.1007/978-1-4612-5010-4_3
Roland S. G. Jones, Electrophysiological Studies of the Possible Role of Trace Amines in Synaptic Function Humana Press. pp. 205- 223 ,(1984) , 10.1007/978-1-4612-5312-9_16
Glen B. Baker, Ronald T. Coutts, Tadimeti S. Rao, T. W. Eric Hall, Ronald G. Micetich, Prodrugs of β-Phenylethylamine and Tryptamine: Studies in the Rat Humana Press. pp. 321- 334 ,(1988) , 10.1007/978-1-4612-4602-2_30
A. V. Juorio, Drug-Induced Changes in the Central Metabolism of Tyramine and Other Trace Monoamines: Their Possible Role in Brain Functions Humana Press. pp. 145- 162 ,(1984) , 10.1007/978-1-4612-5312-9_13
A. V. Juorio, A. J. Greenshaw, A. A. Boulton, Possible Pathways for Some Trace Amine-Containing Neurons Humana Press. pp. 87- 99 ,(1985) , 10.1007/978-1-4612-5010-4_8
A. J. Greenshaw, β-Phenylethylamine: A Functional Role at the Behavioural Level? Humana Press. pp. 351- 374 ,(1984) , 10.1007/978-1-4612-5312-9_31
E M Parker, L X Cubeddu, Comparative effects of amphetamine, phenylethylamine and related drugs on dopamine efflux, dopamine uptake and mazindol binding. Journal of Pharmacology and Experimental Therapeutics. ,vol. 245, pp. 199- 210 ,(1988)
A. A. Boulton, G. B. Baker, THE SUBCELLULAR DISTRIBUTION OF ?-PHENYLETHYLAMINE, p-TYRAMINE AND TRYPTAMINE IN RAT BRAIN Journal of Neurochemistry. ,vol. 25, pp. 477- 481 ,(1975) , 10.1111/J.1471-4159.1975.TB04353.X
A.J. Greenshaw, A.V. Juorio, A.A. Boulton, Behavioral and neurochemical effects of deprenyl and β-phenylethylamine in wistar rats Brain Research Bulletin. ,vol. 15, pp. 183- 189 ,(1985) , 10.1016/0361-9230(85)90134-0