Cellulose-based molecularly imprinted red-blood-cell-like microparticles for the selective capture of cortisol.

作者: Koichiro Hayashi , Hikaru Hayashi , Shota Yamada , Wataru Sakamoto , Toshinobu Yogo

DOI: 10.1016/J.CARBPOL.2018.03.095

关键词:

摘要: Abstract Magnetite-nanoparticle-containing red-blood-cell-like-microparticles (M-RBC-MPs) with a selective ability for trapping cortisol (COR) were synthesized by an electrospray technique of molecularly imprinted ethyl(hydroxyethyl) cellulose (EHEC)-based precursor. The as-synthezied M-RBC-MPs ∼3-μm-disks dent. contained magnetite nanoparticles below 15 nm in diameter, which exhibited magnetization and no room-temperature coercivity. (MI-M-RBC-MPs) passed through pores less than their diameter. MI-M-RBC-MPs selectively trapped COR from solution containing molecules similar to COR, whereas non-imprinted did not trap COR. Furthermore, magnets used capture the water-dispersed flowing tube. Based on above results, may while simultaneously circulating blood, followed removal blood using magnets.

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