Neurological complications of ankylosing spondylitis: neurophysiological assessment

摘要: Studies examined the neurological involvement of ankylosing spondylitis (AS) are limited. This study aimed to assess frequency myelopathy, radiculopathy and myopathy in AS correlating them clinical, radiological laboratory parameters. Included were 24 patients with AS. Axial status was assessed using bath metrology index (BASMI). Patients underwent (a) standard cervical lumbar spine sacroiliac joint radiography, (b) somatosensory (SSEP) magnetic motor (MEP) evoked potentials upper lower limbs, (c) electromyography (EMG) trapezius supraspinatus muscles. Patients’ mean age duration illness 36 5.99 years. Bath score 4.6. Twenty-five percent (n = 6) had manifestations, 8.3% myelopathy 16.7% radiculopathy. Ossification posterior (OPLL) anterior (OALL) longitudinal ligaments found 2) 4.2% 1). About 70.8% 17) ≥1 neurophysiological test abnormalities. Twelve (50%) SSEP abnormalities, seven prolonged central conduction time (CCT) median and/or ulnar nerves suggesting myelopathy. Six delayed peripheral or root latencies at Erb’s interpeak latency (Erb’s-C5) Motor abnormal 54% 13). five (20.8%) MEP limbs respectively. 50% 12) myopathic features Only neuropathic features. We concluded that subclinical complications frequent compared clinically manifest complications. Somatosensory potential useful identify prone develop