Self-poisoning with theophylline. The effect of repeated doses oral charcoal on drug elimination.

摘要: A heavy smoking male patient with moderate to severe theophylline poisoning is presented. Repeated doses of oral charcoal were given in addition usual supportive treatment. During this treatment the elimination half-life drug (T1/2) was 2 hours. The toxic symptoms disappeared rapidly when serum concentration reduced therapeutic range. T1/2 approximately 24 hours same a steady state study without seem increase and should be administered correction metabolic disturbances.