The structure and phase behaviour of α-tocopherol-rich domains in 1-palmitoyl-2-oleoyl-phosphatidylethanolamine
作者： Xiaoyuan Wang , Peter J. Quinn
DOI: 10.1016/J.BIOCHI.2006.07.017
关键词:
摘要: The effect of alpha-tocopherol on the structure and thermotropic phase behaviour 1-palmitoyl-2-oleoyl-phosphatidylethanolamine dispersed in excess water was examined by synchrotron X-ray diffraction differential scanning calorimetry. Small- wide-angle scattering intensity profiles were recorded from mixed dispersions containing up to 20 mol% during temperature scans over range 10-75 degrees C. These showed that a domain enriched separated pure phospholipid mixture. This tends have inverted hexagonal which coexists with bilayers depleted alpha-tocopherol. dimensions are dependent proportion Phase separations also manifest calorimetric evidenced appearance multiple peaks at temperatures corresponding transitions observed experiments. 0-20 as results been used construct partial diagram mixture shows has marked tendency partition form an assumes hexagonal-II structure.
elsevier.com
sci-hub.se 参考文章(32)
V.E. Kagan, E.A. Serbinova, R.A. Bakalova, Ts.S. Stoytchev, A.N. Erin, L.L. Prilipko, R.P. Evstigneeva, Mechanisms of stabilization of biomembranes by alpha-tocopherol. The role of the hydrocarbon chain in the inhibition of lipid peroxidation Biochemical Pharmacology. ,vol. 40, pp. 2403- 2413 ,(1990) , 10.1016/0006-2952(90)90080-5
E Mileykovskaya, W Dowhan, The Cpx two-component signal transduction pathway is activated in Escherichia coli mutant strains lacking phosphatidylethanolamine. Journal of Bacteriology. ,vol. 179, pp. 1029- 1034 ,(1997) , 10.1128/JB.179.4.1029-1034.1997
Valerian E. KAGAN, Peter J. QUINN, The interaction of α-tocopherol and homologues with shorter hydrocarbon chains with phospholipid bilayer dispersions FEBS Journal. ,vol. 171, pp. 661- 667 ,(1988) , 10.1111/J.1432-1033.1988.TB13837.X
J. C. GOMEZ-FERNANDEZ, J. VILLALAIN, F. J. ARANDA, A. ORTIZ, V. MICOL, A. COUTINHO, M. N. BERBERAN-SANTOS, M. J. E. PRIETO, Localization of α‐Tocopherol in Membranesa Annals of the New York Academy of Sciences. ,vol. 570, pp. 109- 120 ,(1989) , 10.1111/J.1749-6632.1989.TB14912.X
John Katsaras, Kenneth R. Jeffrey, Daniel S. C. Yang, Richard M. Epand, Direct evidence for the partial dehydration of phosphatidylethanolamine bilayers on approaching the hexagonal phase Biochemistry. ,vol. 32, pp. 10700- 10707 ,(1993) , 10.1021/BI00091A021
William Stillwell, Tracy Dallman, Alfred C. Dumaual, F. Thomas Crump, Laura J. Jenski, Cholesterol versus alpha-tocopherol: effects on properties of bilayers made from heteroacid phosphatidylcholines Biochemistry. ,vol. 35, pp. 13353- 13362 ,(1996) , 10.1021/BI961058M
Xiaoyuan Wang, Peter J Quinn, Vitamin E and its function in membranes. Progress in Lipid Research. ,vol. 38, pp. 309- 336 ,(1999) , 10.1016/S0163-7827(99)00008-9
E.J. Addink, J. Beintema, Polymorphism of crystalline polypropylene Polymer. ,vol. 2, pp. 185- 193 ,(1961) , 10.1016/0032-3861(61)90021-0
M Paz Sánchez-Migallón, Francisco J Aranda, Juan C Gómez-Fernández, None, The interaction of α-tocopherol with phosphatidylserine vesicles and calcium Biochimica et Biophysica Acta. ,vol. 1281, pp. 23- 30 ,(1996) , 10.1016/0005-2736(95)00300-2
Antonio Ortiz, Francisco J Aranda, Juan C Gómez-Fernández, None, A differential scanning calorimetry study of the interaction of α-tocopherol with mixtures of phospholipids Biochimica et Biophysica Acta. ,vol. 898, pp. 214- 222 ,(1987) , 10.1016/0005-2736(87)90040-X