Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines.

作者: Ewa Gurgul-Convey , Ilir Mehmeti , Thomas Plötz , Anne Jörns , Sigurd Lenzen

DOI: 10.1007/S00125-016-4060-Y

关键词:

摘要: Aims/hypothesis The aim of this study was to perform a detailed analysis cytokine toxicity in the new human EndoC-βH1 beta cell line.

参考文章(45)
Ewa Gurgul-Convey, Martin T. Kaminski, Sigurd Lenzen, Physiological characterization of the human EndoC-βH1 β-cell line Biochemical and Biophysical Research Communications. ,vol. 464, pp. 13- 19 ,(2015) , 10.1016/J.BBRC.2015.05.072
Rikard G. Fred, Camilla Kappe, Adam Ameur, Jing Cen, Peter Bergsten, Phillippe Ravassard, Raphael Scharfmann, Nils Welsh, Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death Molecular and Cellular Endocrinology. ,vol. 414, pp. 53- 63 ,(2015) , 10.1016/J.MCE.2015.07.015
Claes Hellerström, Decio L. Eizirik, Nils Welsh, Boris Margulis, L. A. Håkan Borg, Helena Jernberg Wiklund, Johan Saldeen, Malin Flodström, Maria Alice Mello, Arne Andersson, Daniel G. Pipeleers, Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus. Molecular Medicine. ,vol. 1, pp. 806- 820 ,(1995) , 10.1007/BF03401895
Flora Brozzi, Tarlliza R. Nardelli, Miguel Lopes, Isabelle Millard, Jenny Barthson, Mariana Igoillo-Esteve, Fabio A. Grieco, Olatz Villate, Joana M. Oliveira, Marina Casimir, Marco Bugliani, Feyza Engin, Gökhan S. Hotamisligil, Piero Marchetti, Decio L. Eizirik, Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms. Diabetologia. ,vol. 58, pp. 2307- 2316 ,(2015) , 10.1007/S00125-015-3669-6
Lindsey E. Padgett, Katarzyna A. Broniowska, Polly A. Hansen, John A. Corbett, Hubert M. Tse, The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis Annals of the New York Academy of Sciences. ,vol. 1281, pp. 16- 35 ,(2013) , 10.1111/J.1749-6632.2012.06826.X
Gloria Soldevila, Massimo Buscema, Mala Doshi, Roger F.L. James, Gian Franco Bottazzo, Ricardo Pujol-Borrell, Cytotoxic effect of IFN-γ plus TNF-α on human islet cells Journal of Autoimmunity. ,vol. 4, pp. 291- 306 ,(1991) , 10.1016/0896-8411(91)90025-8
D. Pavlovic, M. C. Chen, L. Bouwens, D. L. Eizirik, D. Pipeleers, Contribution of ductal cells to cytokine responses by human pancreatic islets. Diabetes. ,vol. 48, pp. 29- 33 ,(1999) , 10.2337/DIABETES.48.1.29
THOMAS MANDRUP-POULSEN, Beta cell death and protection. Annals of the New York Academy of Sciences. ,vol. 1005, pp. 32- 42 ,(2003) , 10.1196/ANNALS.1288.005