Brain Adrenergic receptors and resistance to stress

作者: Eric A. Stone , Jane E. Platt

DOI: 10.1016/0006-8993(82)90452-8

关键词:

摘要: Abstract The relationship between brain beta-adrenergic receptors and adaptation to stress was studied in rats subjected repeated restraint stress. found produce a reduction the density of these hypothalamus, cerebral cortex stem. This change first appeared after 4–7 days persisted for duration two-week Adaptation, as judged by resistance anorexic gastric lesion-inducing effects stress, occurred progressively over full period. loss beta-receptors correlate positively with degree adaptation. strongest hypothalamus but also apparent These findings support hypothesis that number adrenergic is one biochemical factors underlying

参考文章(21)
A. B. Dahlstrom, B. E. M. Zetterstrom, NORADRENALINE STORES IN NERVE TERMINALS OF THE SPLEEN: CHANGES DURING HEMORRHAGIC SHOCK. Science. ,vol. 147, pp. 1583- 1585 ,(1965) , 10.1126/SCIENCE.147.3665.1583
Michael J. Zigmond, John A. Harvey, Resistance to central norepinephrine depletion and decreased mortality in rats chronically exposed to electric foot shock. Journal of neuro-visceral relations. ,vol. 31, pp. 373- 381 ,(1970) , 10.1007/BF02312738
Eric A. Stone, Effect of stress on norepinephrine-stimulated cyclic AMP formation in brain slices. Pharmacology, Biochemistry and Behavior. ,vol. 8, pp. 583- 591 ,(1978) , 10.1016/0091-3057(78)90392-1
RICHARD KVETŇANSKÝ, LADISLAV MIKULAJ, Adrenal and urinary catecholamines in rats during adaptation to repeated immobilization stress. Endocrinology. ,vol. 87, pp. 738- 743 ,(1970) , 10.1210/ENDO-87-4-738
J. W. Kebabian, M. Zatz, J. A. Romero, J. Axelrod, Rapid changes in rat pineal beta-adrenergic receptor: alterations in l-(3H)alprenolol binding and adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 72, pp. 3735- 3739 ,(1975) , 10.1073/PNAS.72.9.3735
Sue Ritter, Nancy L. Pelzer, Robert C. Ritter, Absence of glucoprivic feeding after stress suggests impairment of noradrenergic neuron function Brain Research. ,vol. 149, pp. 399- 411 ,(1978) , 10.1016/0006-8993(78)90483-3
Jay M. Weiss, Howard I. Glazer, Larissa A. Pohorecky, John Brick, Neal E. Miller, Effects of chronic exposure to stressors on avoidance-escape behavior and on brain norepinephrine. Psychosomatic Medicine. ,vol. 37, pp. 522- 534 ,(1975) , 10.1097/00006842-197511000-00006
Z. HRUZA, B. W. ZWEIFACH, Catecholamines and dibenzyline in trauma and adaptation to trauma. Journal of Trauma-injury Infection and Critical Care. ,vol. 10, pp. 412- 419 ,(1970) , 10.1097/00005373-197005000-00006
Eric A. Stone, Mechanism of stress-induced subsensitivity to norepinephrine Pharmacology, Biochemistry and Behavior. ,vol. 14, pp. 719- 723 ,(1981) , 10.1016/0091-3057(81)90137-4