作者: Eric A. Stone , Jane E. Platt
DOI: 10.1016/0006-8993(82)90452-8
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摘要: Abstract The relationship between brain beta-adrenergic receptors and adaptation to stress was studied in rats subjected repeated restraint stress. found produce a reduction the density of these hypothalamus, cerebral cortex stem. This change first appeared after 4–7 days persisted for duration two-week Adaptation, as judged by resistance anorexic gastric lesion-inducing effects stress, occurred progressively over full period. loss beta-receptors correlate positively with degree adaptation. strongest hypothalamus but also apparent These findings support hypothesis that number adrenergic is one biochemical factors underlying