Aging and age-related diseases of the ocular lens and vitreous body.

摘要: Reduced quality of life and financial burden due to visual impairment blindness begin increase dramatically when individuals reach the age 40. The major causes age-related vision loss can be traced changes structure function lens, one tissues responsible for focusing light on retina. Age-related nuclear cataracts, which are caused by aggregation condensation proteins, diminish because they impede transmission In addition slow-developing form, cataracts often develop rapidly as a complication ocular surgery, such following vitrectomy or consequence vitreous gel degeneration. Posterior capsular opacification, cataract removal, is proliferation inappropriate accumulation lens epithelial cells surfaces intraocular lenses posterior capsule. Presbyopia accommodative amplitude reduced ability shift focus from far near objects. Onset presbyopia associated with an in hardness change shape response ciliary muscle contraction. Avenues promising research that seek delay prevent these low discussed our current understanding disease pathogenesis some challenges must met achieve success.