The design and physical characteristics of a small animal positron emission tomograph
作者： P M Bloomfield , S Rajeswaran , T J Spinks , S P Hume , R Myers
DOI: 10.1088/0031-9155/40/6/010
关键词:
摘要: A small diameter positron emission tomograph, designed specifically for animal studies, was constructed from existing, commercially available, bismuth germanate (BGO) detectors and electronics. The scanner consists of 16 BGO detector blocks arranged to give a tomograph with 115 mm an axial field view (FOV) 50 mm. Each block is cut produce eight (axial) by seven (radial) individual elements. absence interplane septa enables the acquisition 3D data sets consisting 64 sinograms. 2D set 15 sinograms, direct adjacent cross planes, can be extracted set. Images are reconstructed sinograms using conventional filtered backprojection algorithm. Two methods normalization were investigated, based on either rotating 68Ge rod source, or uniform plane cylindrical 18F phantom. Attenuation emitted photons estimated source. transaxial resolution measured as 2.3 full width at half maximum (FWHM) 5.6 tenth (FWTM) centre FOV, degrading 6.6 4.4 (tangential) FWHM 10.4 14.4 FWTM 40.0 FOV. slice 4.3 FWHM, 10.3 10.6 20.0 scatter fraction 31.0% 250-850 keV, line source centred in 60 diameter, water-filled phantom, reducing 20.4% 13.8% lower energy discrimination increased 380 keV 450 respectively. count rate performance noise equivalent method, linearity dead time correction confirmed over rates encountered during routine scanning. In mode, absolute sensitivity 9948 counts s-1 MBq-1 8284 380-850 6280 450-850 keV.
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