Radiothérapie des carcinomes canalaires in situ : impact du complément d’irradiation du lit tumoral

作者: D. Azria , H. Auvray , I. Barillot , P. Baumann , A. Benyoucef

DOI: 10.1016/J.CANRAD.2008.07.005

关键词:

摘要: Ductal carcinoma in situ is defined as breast cancer confined to the ducts of without evidence penetration basement membrane. Local treatment quality represents one most prognostic factors half recurrences are invasive diseases. The main goal adjuvant radiotherapy after conservative surgery decrease local and permit conservation with low treatment-induced sequelae. Several randomized trials have established impact 50 Gy whole terms control. Nevertheless, no trial still available concerning role boost this disease. In review, we present updated results literature detail French multicentric evaluating a 16 delivered 25 fractions 33 days. This protocol will start inclusions October 2008.

参考文章(22)
B Fisher, J Dignam, N Wolmark, E Mamounas, J Costantino, W Poller, E R Fisher, D L Wickerham, M Deutsch, R Margolese, N Dimitrov, M Kavanah, Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17. Journal of Clinical Oncology. ,vol. 16, pp. 441- 452 ,(1998) , 10.1200/JCO.1998.16.2.441
P. Fourneret, X. Artignan, J. De Cornulier, D. Pasquier, M.-H. Panh, R. Payan, H. Kolodié, F. Vincent, D. Fric, P. Bernard, M. Colona, M. Bolla, Analyse rétrospective de 108 carcinomes canalaires in situ mammaires traités par association radiochirurgicale Cancer Radiotherapie. ,vol. 10, pp. 550- 558 ,(2006) , 10.1016/J.CANRAD.2006.06.010
Bernard Fisher, James Dignam, Norman Wolmark, D Lawrence Wickerham, Edwin R Fisher, Eleftherios Mamounas, Roy Smith, Mirsada Begovic, Nikolay V Dimitrov, Richard G Margolese, Carl G Kardinal, Maureen T Kavanah, Louis Fehrenbacher, Robert H Oishi, None, Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial The Lancet. ,vol. 353, pp. 1993- 2000 ,(1999) , 10.1016/S0140-6736(99)05036-9
Lawrence J Solin, Alain Fourquet, Frank A Vicini, Bruce Haffty, Marie Taylor, Beryl McCormick, Marsha McNeese, Lori J Pierce, Christine Landmann, Ivo A Olivotto, Jacques Borger, Jung-Soo Kim, Anne de la Rochefordiere, Delray J Schultz, Mammographically detected ductal carcinoma in situ of the breast treated with breast-conserving surgery and definitive breast irradiation: long-term outcome and prognostic significance of patient age and margin status. International Journal of Radiation Oncology Biology Physics. ,vol. 50, pp. 991- 1002 ,(2001) , 10.1016/S0360-3016(01)01517-6
Virginia L Ernster, John Barclay, Karla Kerlikowske, Deborah Grady, I Craig Henderson, Incidence of and Treatment for Ductal Carcinoma In Situ of the Breast JAMA: The Journal of the American Medical Association. ,vol. 275, pp. 913- 918 ,(1996) , 10.1001/JAMA.1996.03530360023033
Stefan O. Emdin, Bengt Granstrand, Anita Ringberg, Kerstin Sandelin, Lars-Gunnar Arnesson, Hans Nordgren, Harald Anderson, Hans Garmo, Lars Holmberg, Arne Wallgren, , SweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening Acta Oncologica. ,vol. 45, pp. 536- 543 ,(2006) , 10.1080/02841860600681569
Alice Y Ho, David P Atencio, Sheila Peters, Richard G Stock, Silvia C Formenti, Jamie A Cesaretti, Sheryl Green, Bruce Haffty, Karen Drumea, Larisa Leitzin, Abraham Kuten, David Azria, Mahmut Ozsahin, Jens Overgaard, Christian N Andreassen, Cynthia S Trop, Janelle Park, Barry S Rosenstein, None, Genetic Predictors of Adverse Radiotherapy Effects: The Gene-PARE project International Journal of Radiation Oncology*Biology*Physics. ,vol. 65, pp. 646- 655 ,(2006) , 10.1016/J.IJROBP.2006.03.006
D Azria, S Gourgou, W J Sozzi, A Zouhair, R O Mirimanoff, A Kramar, C Lemanski, J B Dubois, G Romieu, A Pelegrin, M Ozsahin, Concomitant use of tamoxifen with radiotherapy enhances subcutaneous breast fibrosis in hypersensitive patients. British Journal of Cancer. ,vol. 91, pp. 1251- 1260 ,(2004) , 10.1038/SJ.BJC.6602146
Mahmut Ozsahin, Nigel E.A. Crompton, Sophie Gourgou, Andrew Kramar, Ling Li, YuQuan Shi, Wendy Jeanneret Sozzi, Abderrahim Zouhair, René O. Mirimanoff, David Azria, CD4 and CD8 T-Lymphocyte Apoptosis Can Predict Radiation-Induced Late Toxicity: A Prospective Study in 399 Patients Clinical Cancer Research. ,vol. 11, pp. 7426- 7433 ,(2005) , 10.1158/1078-0432.CCR-04-2634