Prognostic value of chloride channel accessory mRNA expression in colon cancer

作者: Xiaohang Pan , Qiaoqi Wang , Chenfei Xu , Ling Yan , Sen Pang

DOI: 10.3892/OL.2019.10615

关键词:

摘要: Chloride channel accessory (CLCA) is a gene family that encode Ca2+ activated chloride channels, which make substantial contribution to various diseases. The aim of the present study was investigate prognostic value CLCA expression in colon cancer. In an attempt elucidate mRNA prognosis patients with cancer, data 438 cancer were analyzed. source Cancer Genome Atlas, and it identified high levels CLCA1 CLCA2 associated favorable overall survival (OS) time As revealed by joint effects analysis, co-occurrence OS genes investigated using set enrichment analysis. results bioinformatics analysis demonstrated These findings suggest are potential biomarkers for Furthermore, combining can enhance sensitivity prediction

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