Controlling the double helix

作者: Gary Felsenfeld , Mark Groudine

DOI: 10.1038/NATURE01411

关键词:

摘要: Chromatin is the complex of DNA and proteins in which genetic material packaged inside cells organisms with nuclei. structure dynamic exerts profound control over gene expression other fundamental cellular processes. Changes its can be inherited by next generation, independent sequence itself.

参考文章(51)
Andrew J. Bannister, Philip Zegerman, Janet F. Partridge, Eric A. Miska, Jean O. Thomas, Robin C. Allshire, Tony Kouzarides, Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. ,vol. 410, pp. 120- 124 ,(2001) , 10.1038/35065138
Erik D. Andrulis, Aaron M. Neiman, David C. Zappulla, Rolf Sternglanz, Perinuclear localization of chromatin facilitates transcriptional silencing Nature. ,vol. 394, pp. 592- 595 ,(1998) , 10.1038/29100
Monika Lachner, Dónal O'Carroll, Stephen Rea, Karl Mechtler, Thomas Jenuwein, Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. ,vol. 410, pp. 116- 120 ,(2001) , 10.1038/35065132
Amy T. Hark, Christopher J. Schoenherr, David J. Katz, Robert S. Ingram, John M. Levorse, Shirley M. Tilghman, CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus Nature. ,vol. 405, pp. 486- 489 ,(2000) , 10.1038/35013106
Adam C. Bell, Gary Felsenfeld, Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene Nature. ,vol. 405, pp. 482- 485 ,(2000) , 10.1038/35013100
Geeta J. Narlikar, Hua-Ying Fan, Robert E. Kingston, Cooperation between Complexes that Regulate Chromatin Structure and Transcription Cell. ,vol. 108, pp. 475- 487 ,(2002) , 10.1016/S0092-8674(02)00654-2
Nicole J. Francis, Robert E. Kingston, Mechanisms of transcriptional memory Nature Reviews Molecular Cell Biology. ,vol. 2, pp. 409- 421 ,(2001) , 10.1038/35073039
Michael Grunstein, Molecular model for telomeric heterochromatin in yeast Current Opinion in Cell Biology. ,vol. 9, pp. 383- 387 ,(1997) , 10.1016/S0955-0674(97)80011-7