Possible Association and Risk Factors of Blastocystis Infection and Colorectal Cancers in Western Iran

摘要: Background: Recently, infection has been considered one of the most important causes cancers because a large number cases cancer with infectious origin was reported. Objectives: The present investigation aimed to evaluate prevalence and risk factors Blastocystis hominis in patients colorectal comparison healthy individuals. Methods: descriptive case-control study performed on 67 individuals attending general hospitals Lorestan Province, Western Iran from October 2017 August 2018. Colorectal were diagnosed by an experienced gastroenterologist. A fresh stool specimen collected each subject sterile labeled container. specimens tested microscopically using saline iodine wet preparations, then stained trichrome stain according manufacturer’s instruction find B. forms. DNA samples extracted specific primer-polymerase chain reaction (PCR) performed. Results: Among patients, found 16 (23.9%) whereas participants, 6 (9%) found, indicating significant difference (P < 0.001) among participants case control groups. By multifactorial logistic regression models, agriculture activity (0.24; 95% CI: 0.075 - 0.809), as well consumption unwashed fruit vegetables (0.136; 0.040 0.459), significantly related homonis infection. All 22 positive (16 people) also PCR method, presence accuracy microscopic examination, extraction, reaction. Conclusions: obtained findings revealed that may strongly link human given novel information about role progress cancer. Nevertheless, more investigations are required obtain accurate this suggestion.