Laterality, maldescent, trauma and other clinical factors in the epidemiology of testis cancer in Victoria, Australia.

摘要: Clinical factors were studied in a population based survey of 1,116 cases testicular neoplasms Victoria, Australia, between 1950 and 1978. The ratio right to left sided tumours was 54:46, but the side predominated among sarcomas (P = 0.006), older men. relative risk (RR) for men with unilateral maldescent 15 (CI 10-23) bilateral 33 20-55) (odds 1.4, CI 0.5-4, P 0.7). Calculations per testis showed an elevated both maldescended (RR 28, 19-41, less than 0.0001) normally descended 3, 1.2-6, 0.04). RR abdominal 55 36-83) compared 7 4-11) those inguinal 8, 3-20, 0.0001). Seminomas more common nonseminomas (NSGCT) history 1.7, 1.1-3, 0.02) also corrected cryptorchids uncorrected 0.005). diagnosed at earlier median age cryptorchid testes 0.03) 0.001). Maldescent associated hernia Twenty-eight cent patients recorded trauma higher proportion NSGCT seminomas 0.03). Prior malignancies reported nine patients, 3.6 expected; prostate cancer (2) malignant melanoma greatest contributors excess.