Milk ribonuclease-enriched lactoferrin induces positive effects on bone turnover markers in postmenopausal women

摘要: Current treatments for postmenopausal osteoporosis suffer from side effects. Safe and natural milk proteins, ribonuclease, lactoferrin promote formation of new capillaries bone formation. A ribonuclease-enriched supplement studied here, demonstrates significant reduction in resorption increase formation, towards restoring the balance turnover within 6 months. Osteoporosis, a major health issue among women, causes increased reduced angiogenesis could also contribute to this imbalance. such as hormone replacement therapy bisphosphonates have drawbacks severe Milk ribonuclease (RNase) is known (LF) stimulate by osteoblasts. We examine effect on women. total 38 healthy, aged 45 60 years were randomized into placebo or RNAse-enriched-LF (R-ELF) groups. The status was monitored assessing markers, serum N-telopeptides (NTx), urine deoxypyridinoline (Dpd) crosslinks bone-specific alkaline phosphatase (BAP), osteocalcin (OC). R-ELF supplementation demonstrated decrease Dpd levels 14% (19% placebo) NTx maintained at 24% baseline (41% placebo), while BAP OC showed 45% 16% elevation (25% 5% placebo). statistically osteoblastic restore short period.