Factors that may influence estimated glomerular filtration rate in patients with excellent graft function 10 years posttransplant.

作者: J. Guerra , M. Raimundo , C. Teixeira , A. Santana , A. Cortesão

DOI: 10.1016/J.TRANSPROCEED.2013.03.003

关键词:

摘要: Abstract Background Donor age, cold ischemia time, delayed graft function (DGF), prior sensitization, HLA mismatches, acute rejection episodes, glomerular disease and viral nephropathy are some factors that shorten survival. Patients with excellent at 10 years posttransplant have probably successfully overcome these detrimental factors. The effect of initial functional renal mass is associated this outcome. objective the present study was to identify show predictive value for population patients posttransplantation. methods This retrospective observational included 117 transplanted from deceased donors. They all presented filtration rates (GFR) ≥ 40 mL/min. were stratified as group I (n = 56) estimated GFR Results age DGF significantly different between two groups upon univariate analysis. Multivariate logistic regression analysis showed only donor be independently an eGFR mL/min 1st 10th year correlated (P .04). deterioration greater among than II (6.7 vs 0.23 mL/min; P .007). Conclusion most significant factor years.

参考文章(12)
K. E. Lamb, S. Lodhi, H.-U. Meier-Kriesche, Long-term renal allograft survival in the United States: a critical reappraisal. American Journal of Transplantation. ,vol. 11, pp. 450- 462 ,(2011) , 10.1111/J.1600-6143.2010.03283.X
C. Traynor, A. Jenkinson, Y. Williams, P. O’Kelly, D. Hickey, M. Denton, C. Magee, P. J. Conlon, Twenty-year survivors of kidney transplantation. American Journal of Transplantation. ,vol. 12, pp. 3289- 3295 ,(2012) , 10.1111/J.1600-6143.2012.04236.X
JOON H. HONG, KHAN SHIRANI, ABDUL ARSHAD, ISMAIL PARSA, ARTHUR MATAS, ROLAND J. ADAMSONS, KHALID M. H. BUTT, Influence of cadaver donor age on the success of kidney transplants. Transplantation. ,vol. 32, pp. 532- 534 ,(1981) , 10.1097/00007890-198112000-00017
Stephen R. Kerr, Kristen J. Gillingham, Eric M. Johnson, Arthur J. Matas, Living donors >55 years: to use or not to use? Transplantation. ,vol. 67, pp. 999- 1004 ,(1999) , 10.1097/00007890-199904150-00011
G. Grosso, D. Corona, A. Mistretta, D. Zerbo, N. Sinagra, A. Giaquinta, S. Cimino, B. Ekser, G. Giuffrida, A. Leonardi, R. Gula, P. Veroux, M. Veroux, Delayed Graft Function and Long-Term Outcome in Kidney Transplantation Transplantation Proceedings. ,vol. 44, pp. 1879- 1883 ,(2012) , 10.1016/J.TRANSPROCEED.2012.06.044
Julio Pascual, Javier Zamora, John D. Pirsch, A systematic review of kidney transplantation from expanded criteria donors. American Journal of Kidney Diseases. ,vol. 52, pp. 553- 586 ,(2008) , 10.1053/J.AJKD.2008.06.005
A. J. Matas, K. J. Gillingham, A. Humar, R. Kandaswamy, D. E. R. Sutherland, W. D. Payne, T. B. Dunn, J. S. Najarian, 2202 Kidney Transplant Recipients with 10 Years of Graft Function: What Happens Next? American Journal of Transplantation. ,vol. 8, pp. 2410- 2419 ,(2008) , 10.1111/J.1600-6143.2008.02414.X
Disaya Chavalitdhamrong Disaya Chavalitdhamrong, J Gill, S Takemoto, BR Madhira, YW Cho, T Shah, S Bunnapradist, Patient and graft outcomes from deceased kidney donors age 70 years and older: an analysis of the Organ Procurement Transplant Network/United Network of Organ Sharing database. Transplantation. ,vol. 85, pp. 1573- 1579 ,(2008) , 10.1097/TP.0B013E31817059A1
R Emiroğlu, MC Yagmurdur, F Karakayali, C Haberal, U Ozcelik, T Colak, M Haberal, None, Role of Donor Age and Acute Rejection Episodes on Long-Term Graft Survival in Cadaveric Kidney Transplantations Congress of the Middle East Society for Organ Transplantation (MESOT). ,vol. 37, pp. 2954- 2956 ,(2005) , 10.1016/J.TRANSPROCEED.2005.08.038