Transdermal Nicotine Therapy and Primary Care: Importance of Counseling, Demographic, and Participant Selection Factors on 1-Year Quit Rates

摘要: OBJECTIVE To evaluate the smoking cessation efficacy of nicotine patch therapy as an adjunct to low-intensity, primary care intervention. DESIGN Randomized, placebo-controlled, double-blind, multisite trial. SETTINGS Twenty-one sites in Nebraska. PATIENTS A total 369 smokers 20 or more cigarettes per day. INTERVENTION Two brief visits for intervention with 10 weeks active placebo-patch therapy. MAIN OUTCOME MEASURES Confirmed self-reported abstinence 3, 6, and 12 months after quit RESULTS Compared placebo control subjects, participants assigned patches had higher 3-month (23.4% vs 11.4%; P = 7), 1-year rates were significantly group (19.1%) compared (5.0%) (chi 2 10.7; .001). However, there was no significant difference low Fagerstrom scores (< 7). CONCLUSIONS Nicotine enhanced 6 month The highest achieved by who specifically contacted site enroll study obtain a prescription patches. Differences participant selection factors may account, part, lower associated Duration counseling, patient age, be important related long-term success