Accuracy of positron emission tomography in mediastinal node assessment in coal workers with lung cancer

作者: Ozkan Saydam , Mertol Gokce , Ali Kilicgun , Ozgur Tanriverdi

DOI: 10.1007/S12032-011-9879-Y

关键词:

摘要: The purpose of this study was to explore the accuracy 18F-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) in assessment mediastinal lymph node coal workers who had non-small cell lung cancer. We retrospectively reviewed 42 retired cancer without distant metastasis, between May 2007 and 2010. Regarding nodes, when standard uptake value greater than 2.5, it considered “malignancy positive.” After histological examination anthracotic metastatic ones were detected. results PET/CT analyzed determine its accuracy. Of these patients, detected 47 positive nodes 24 patients with a mean SUV maximum 6.2 (2.6–13.8). One hundred thirty-one foci dissected. sensitivity, specificity, predictive value, negative FDG-PET/CT detecting nodal metastases 84% (16/19), 65% (15/23), 66% (16/24), 83% (15/18), 74% (31/42) on per-patient basis, respectively. Mediastinal staging is insufficient due high false-positive rates presence pneumoconiosis. In an invasive technique such as mediastinoscopy seems mandatory for confirmation ipsilateral or contralateral metastasis.

参考文章(24)
Carolyn E Reed, David H Harpole, Katherine E Posther, Sandra L Woolson, Robert J Downey, Bryan F Meyers, Robert T Heelan, Homer A MacApinlac, Sin-Ho Jung, Gerard A Silvestri, Barry A Siegel, Valerie W Rusch, Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non–small cell lung cancer The Journal of Thoracic and Cardiovascular Surgery. ,vol. 126, pp. 1943- 1951 ,(2003) , 10.1016/J.JTCVS.2003.07.030
J. Albes, R. Lietzenmayer, U. Schott, E. Schülen, M. Wehrmann, G. Ziemer, Improvement of non-small-cell lung cancer staging by means of positron emission tomography. Thoracic and Cardiovascular Surgeon. ,vol. 47, pp. 42- 47 ,(1999) , 10.1055/S-2007-1013107
Sung Shine Shim, Kyung Soo Lee, Byung-Tae Kim, Myung Jin Chung, Eun Jung Lee, Joungho Han, Joon Young Choi, O Jung Kwon, Young Mog Shim, Seonwoo Kim, Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging. Radiology. ,vol. 236, pp. 1011- 1019 ,(2005) , 10.1148/RADIOL.2363041310
Robert C. Stadalnik, Siema M. Bakheet, John Powe, Benign causes of 18-FDG uptake on whole body imaging. Seminars in Nuclear Medicine. ,vol. 28, pp. 352- 358 ,(1998) , 10.1016/S0001-2998(98)80038-X
Jun Konishi, Koichi Yamazaki, Eriko Tsukamoto, Nagara Tamaki, Yuya Onodera, Toshiyuki Otake, Toshiaki Morikawa, Ichiro Kinoshita, Hirotoshi Dosaka-Akita, Masaharu Nishimura, Mediastinal lymph node staging by FDG-PET in patients with non-small cell lung cancer: analysis of false-positive FDG-PET findings. Respiration. ,vol. 70, pp. 500- 506 ,(2003) , 10.1159/000074207
MOTOO KATABAMI, HIROTOSHI DOSAKA-AKITA, KOICHI HONMA, YOSHIAKI SAITOH, KIYONOBU KIMURA, YOSHIKAZU UCHIDA, HIROSHI MIKAMI, YUTAKA OHSAKI, YOSHIKAZU KAWAKAMI, KOKICHI KIKUCHI, Pneumoconiosis-related lung cancers: preferential occurrence from diffuse interstitial fibrosis-type pneumoconiosis. American Journal of Respiratory and Critical Care Medicine. ,vol. 162, pp. 295- 300 ,(2000) , 10.1164/AJRCCM.162.1.9906138
Robert J Cerfolio, Buddhiwardhan Ojha, Ayesha S Bryant, Cynthia S Bass, Alfred A Bartalucci, James M Mountz, The role of FDG-PET scan in staging patients with nonsmall cell carcinoma The Annals of Thoracic Surgery. ,vol. 76, pp. 861- 866 ,(2003) , 10.1016/S0003-4975(03)00888-9
Ludwig G. Strauss, Fluorine-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients. European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 23, pp. 1409- 1415 ,(1996) , 10.1007/BF01367602
Matthew Reichert, Eric S. Bensadoun, PET Imaging in Patients with Coal Workers Pneumoconiosis and Suspected Malignancy Journal of Thoracic Oncology. ,vol. 4, pp. 649- 651 ,(2009) , 10.1097/JTO.0B013E31819D4778