Biosynthetic building blocks of taxanes

作者: Lolita O. Zamir , Maria E. Nedea , François X. Garneau

DOI: 10.1016/S0040-4039(00)79141-6

关键词:

摘要: Abstract Radiolabelling feeding experiments have confirmed that acetate, mevalonate and phenylalanie represent the biosynthetic building blocks of Taxus canadensis taxanes.

参考文章(8)
Nicholas C. Wheeler, Keith Jech, Susan Masters, Susan W. Brobst, A. Belinda Alvarado, Andrew J. Hoover, Kenneth M. Snader, Effects of genetic, epigenetic, and environmental factors on taxol content in Taxus brevifolia and related species. Journal of Natural Products. ,vol. 55, pp. 432- 440 ,(1992) , 10.1021/NP50082A005
Françoise Guéritte-Voegelein, Daniel Guénard, Pierre Potier, Taxol and derivatives: a biogenetic hypothesis. Journal of Natural Products. ,vol. 50, pp. 9- 18 ,(1987) , 10.1021/NP50049A002
Robin V. Platt, Clive T. Opie, Edwin Haslam, Biosynthesis of flavan-3-ols and other secondary plant products from (2S)phenylalanine Phytochemistry. ,vol. 23, pp. 2211- 2217 ,(1984) , 10.1016/S0031-9422(00)80522-1
Keith M. Witherup, Sally A. Look, Michael W. Stasko, Thomas J. Ghiorzi, Gary M. Muschik, Gordon M. Cragg, Taxus spp. needles contain amounts of taxol comparable to the bark of Taxus brevifolia: analysis and isolation. Journal of Natural Products. ,vol. 53, pp. 1249- 1255 ,(1990) , 10.1021/NP50071A017
Edward Leete, George B. Bodem, The biosynthesis of 3-dimethylamino-3-phenyl- propanoic acid in yew Tetrahedron Letters. ,vol. 7, pp. 3925- 3927 ,(1966) , 10.1016/S0040-4039(00)70002-5
J. N. Baxter, B. Lythgoe, B. Scales, R. M. Scrowston, S. Trippett, 575. Taxine. Part I. Isolation studies and the functional groups of O-cinnamoyltaxicin-I Journal of the Chemical Society (Resumed). pp. 2964- 2971 ,(1962) , 10.1039/JR9620002964