The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle

作者: Michaël Jeanblanc , Marc Mousli , Raphaël Hopfner , Kawtar Bathami , Nadine Martinet

DOI: 10.1038/SJ.ONC.1208878

关键词:

摘要: … and may alter ubiquitination of histone H3 and consequently gene transcription. Therefore, pRB degradation and/or phosphorylation would facilitate histone H3 ubiquitination by ICBP90…

参考文章(30)
Yoshimi Arima, Toru Hirota, Christian Bronner, Marc Mousli, Toshiyoshi Fujiwara, Shin‐ichiro Niwa, Hiroyuki Ishikawa, Hideyuki Saya, None, Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition. Genes to Cells. ,vol. 9, pp. 131- 142 ,(2004) , 10.1111/J.1356-9597.2004.00710.X
Emma S Hickman, M Cristina Moroni, Kristian Helin, The role of p53 and pRB in apoptosis and cancer Current Opinion in Genetics & Development. ,vol. 12, pp. 60- 66 ,(2002) , 10.1016/S0959-437X(01)00265-9
Graeme J. Walker, José F. Flores, J. Michael Glendening, Amy (Hsui-Ti) Lin, Isabel D. C. Markl, Jane W. Fountain, Virtually 100% of melanoma cell lines harbor alterations at the DNA level withinCDKN2A, CDKN2B, or one of their downstream targets Genes, Chromosomes and Cancer. ,vol. 22, pp. 157- 163 ,(1998) , 10.1002/(SICI)1098-2264(199806)22:2<157::AID-GCC11>3.0.CO;2-N
F. D. Hong, H. J. Huang, H. To, L. J. Young, A. Oro, R. Bookstein, E. Y. Lee, W. H. Lee, Structure of the human retinoblastoma gene. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 5502- 5506 ,(1989) , 10.1073/PNAS.86.14.5502
Sabyasachi Bhattacharya, Judit Garriga, Joaquim Calbó, Thomas Yong, Dale S Haines, Xavier Graña, SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells Oncogene. ,vol. 22, pp. 2443- 2451 ,(2003) , 10.1038/SJ.ONC.1206339
Soren J. Nielsen, Robert Schneider, Uta-Maria Bauer, Andrew J. Bannister, Ashby Morrison, Donal O'Carroll, Ron Firestein, Michael Cleary, Thomas Jenuwein, Rafael E. Herrera, Tony Kouzarides, Rb targets histone H3 methylation and HP1 to promoters Nature. ,vol. 412, pp. 561- 565 ,(2001) , 10.1038/35087620
Motoko Unoki, Toshihiko Nishidate, Yusuke Nakamura, ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene. ,vol. 23, pp. 7601- 7610 ,(2004) , 10.1038/SJ.ONC.1208053
Gang Wang, Robin Miskimins, W.Keith Miskimins, Mimosine Arrests Cells in G1 by Enhancing the Levels of p27Kip1 Experimental Cell Research. ,vol. 254, pp. 64- 71 ,(2000) , 10.1006/EXCR.1999.4743