Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis

作者: M V Apte , P S Haber , S J Darby , S C Rodgers , G W McCaughan

DOI: 10.1136/GUT.44.4.534

关键词:

摘要: … to show that these cells have the ability … pancreatic stellate cells have not yet been defined. Therefore, the aims of this study were to determine whether cultured pancreatic stellate cells: (…

参考文章(38)
Gressner Am, Cytokines and cellular crosstalk involved in the activation of fat-storing cells. Journal of Hepatology. ,vol. 22, pp. 28- 36 ,(1995)
Heinz Furthmayr, Immunochemistry of the extracellular matrix CRC Press. ,(1982)
Vay Liang W. Go, The Pancreas : biology, pathobiology, and disease Raven Press. ,(1993)
M. Pinzani, A. Caligiuri, R. Defranco, H. Herbst, R. G. Romanelli, S. Milani, G. Pellegrini, P. Gentilini, A. Gentilini, C. Grappone, Dac Vinh Ngo, Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. American Journal of Pathology. ,vol. 148, pp. 785- 800 ,(1996)
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
Jean-Luc Van Laethem, Jacques Deviere, Anne Resibois, Fabienne Rickaert, Pascale Vertongen, Haruo Ohtani, Michel Cremer, Kohei Miyazono, Patrick Robberecht, Localization of transforming growth factor β1 and its latent binding protein in human chronic pancreatitis Gastroenterology. ,vol. 108, pp. 1873- 1881 ,(1995) , 10.1016/0016-5085(95)90152-3
A Menke, H Yamaguchi, TM Gress, G Adler, Extracellular matrix is reduced by inhibition of transforming growth factor beta1 in pancreatitis in the rat Gastroenterology. ,vol. 113, pp. 295- 303 ,(1997) , 10.1016/S0016-5085(97)70107-0
M V Apte, P S Haber, T L Applegate, I D Norton, G W McCaughan, M A Korsten, R C Pirola, J S Wilson, Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture Gut. ,vol. 43, pp. 128- 133 ,(1998) , 10.1136/GUT.43.1.128
T. GRESS, F. MÜLLER-PILLASCH, H.-P. ELSÄSSER, M. BACHEM, C. FERRARA, H. WEIDENBACH, M. LERCH, G. ADLER, Enhancement of transforming growth factor β1 expression in the rat pancreas during regeneration from caerulein-induced pancreatitis European Journal of Clinical Investigation. ,vol. 24, pp. 679- 685 ,(1994) , 10.1111/J.1365-2362.1994.TB01060.X
S B Jakowlew, J E Mead, D Danielpour, J Wu, A B Roberts, N Fausto, Transforming growth factor-beta (TGF-beta) isoforms in rat liver regeneration: messenger RNA expression and activation of latent TGF-beta. Cell Regulation. ,vol. 2, pp. 535- 548 ,(1991) , 10.1091/MBC.2.7.535