Low Treatment Adherence in Pubertal Children Treated with Thyroxin or Growth Hormone
作者： Nina Lass , Thomas Reinehr
DOI: 10.1159/000437305
关键词:
摘要: Background: Treatment outcome depends largely on treatment adherence (TA). However, studies analyzing TA in chronic endocrine diseases are scarce and controversial childhood. Patients Methods: We studied 103 children treated subcutaneously with growth hormone (GH) 97 orally thyroxin. was calculated based the prescription refill rates. The number of GH injections recorded by an autoinjector device 23 GH. Results: correlation between rates very good (p 3 doses/week). Discussion: Puberty self-administration drugs were negative predictors TA. Therefore, puberty, prevention efforts should be undertaken to improve TA, especially when adolescents administer their themselves.
karger.com 
sci-hub.se 参考文章(23)
Cole Tj, The LMS method for constructing normalized growth standards. European Journal of Clinical Nutrition. ,vol. 44, pp. 45- 60 ,(1990)
Patricia Kennedy, Kathleen Costello, Jo Scanzillo, Recognizing nonadherence in patients with multiple sclerosis and maintaining treatment adherence in the long term. The Medscape Journal of Medicine. ,vol. 10, pp. 225- ,(2008)
W. A. Marshall, J. M. Tanner, Variations in the Pattern of Pubertal Changes in Boys Archives of Disease in Childhood. ,vol. 45, pp. 13- 23 ,(1970) , 10.1136/ADC.45.239.13
Fritz Haverkamp, Lotta Johansson, Hervé Dumas, Shirley Langham, Maithe Tauber, Dag Veimo, Francesco Chiarelli, Observations of nonadherence to recombinant human growth hormone therapy in clinical practice Clinical Therapeutics. ,vol. 30, pp. 307- 316 ,(2008) , 10.1016/J.CLINTHERA.2008.02.017
R R Kapoor, S A Burke, S E Sparrow, I A Hughes, D B Dunger, K K Ong, C L Acerini, Monitoring of concordance in growth hormone therapy Archives of Disease in Childhood. ,vol. 93, pp. 147- 148 ,(2008) , 10.1136/ADC.2006.114249
Michael B. Ranke, Anders Lindberg, Primus E. Mullis, Mitchell E. Geffner, Toshi Tanaka, Wayne S. Cutfield, Maïthé Tauber, David Dunger, Towards optimal treatment with growth hormone in short children and adolescents: evidence and theses. Hormone Research in Paediatrics. ,vol. 79, pp. 51- 67 ,(2013) , 10.1159/000347121
Wayne S Cutfield, José GB Derraik, Alistair J Gunn, Kyle Reid, Theresa Delany, Elizabeth Robinson, Paul L Hofman, None, Non-Compliance with Growth Hormone Treatment in Children Is Common and Impairs Linear Growth PLoS ONE. ,vol. 6, pp. e16223- ,(2011) , 10.1371/JOURNAL.PONE.0016223
J. Dahlgren, D. Veimo, L. Johansson, I. Bech, Patient acceptance of a novel electronic auto-injector device to administer recombinant human growth hormone: results from an open-label, user survey of everyday use. Current Medical Research and Opinion. ,vol. 23, pp. 1649- 1655 ,(2007) , 10.1185/030079907X210589
Ron Rosenfeld, Bert Bakker, Compliance and persistence in pediatric and adult patients receiving growth hormone therapy. Endocrine Practice. ,vol. 14, pp. 143- 154 ,(2008) , 10.4158/EP.14.2.143
Cameron K. Tebbi, K. Michael Cummings, Michael A. Zevon, Leasel Smith, Mary Richards, Janis Mallon, Compliance of pediatric and adolescent cancer patients Cancer. ,vol. 58, pp. 1179- 1184 ,(1986) , 10.1002/1097-0142(19860901)58:5<1179::AID-CNCR2820580534>3.0.CO;2-E